报告人：James Wohlschlegel
题目： Proteomic Insights into Iron Metabolism and DNA Repair
时间：2015年7月6日上午9:00
地点：林学中心会议室
报告人简历
James Wohlschlegel，加州大学洛杉矶分校大卫格芬医学院副教授。主要研究方向：蛋白组学。
已发表文章
Vashisht AA, Zumbrennen KB, Huang X, Powers DN, Durazo A, Sun D, Bhaskaran N, Persson A, Uhlen M, Sangfelt O, Spruck C, Leibold EA, Wohlschlegel JA. Science. Control of iron homeostasis by an iron-regulated ubiquitin ligase 2009 Oct 30;326(5953):718-21
Vashisht AA, Yu CC, Sharma T, Ro K, Wohlschlegel JA.The Association of the Xeroderma Pigmentosum Group D DNA Helicase (XPD) with Transcription Factor IIH Is Regulated by the Cytosolic Iron-Sulfur Cluster Assembly Pathway. J Biol Chem. 2015 May 29;290(22):14218-25
Xue Y, Vashisht AA, Tan Y, Su T, Wohlschlegel JA.PRB1 is required for clipping of the histone H3 N terminal tail in Saccharomyces cerevisiae. PLoS One. 2014 Feb 28;9(2):e90496
Xuehua Zhong, Christopher J. Hale, Minh Nguyen, Israel Ausin, Martin Groth, Jonathan Hetzel, Ajay A. Vashisht, Ian R. Henderson, James A. Wohlschlegel, and Steven E. Jacobsen. (2015) DOMAINS REARRANGED METHYLTRANSFERASE3 controls DNA methylation and regulates RNA polymerase V transcript abundance in Arabidopsis. Proc. Nat. Acad. Sci. U. S. A., 112:911-916
Guillaume Moissiard, Sylvain Bischof, Dylan Husmann, William A. Pastor, Christopher J. Hale, Linda Yen, Hume Stroud, Ashot Papikian, Ajay A. Vashisht, James A. Wohlschlegel, and Steven E. Jacobsen. (2014) Transcriptional gene silencing by Arabidopsis microrchidia homologues involves the formation of heteromers. Proc. Nat. Acad. Sci. U. S. A., 111:7474-7479
Martin Groth, Hume Stroud, Suhua Feng, Maxim V. C. Greenberg, Ajay A. Vashisht, James A. Wohlschlegel, Steven E. Jacobsen, and Israel Ausin. (2014) SNF2 chromatin remodeler-family proteins FRG1 and -2 are required for RNA-directed DNA methylation. Proc. Nat. Acad. Sci. U. S. A., 111:17666-17671.
Xuehua Zhong, Jiamu Du, Christopher J. Hale, Javier Gallego-Bartolome, Suhua Feng, Ajay A. Vashisht, Joanne Chory, James A. Wohlschlegel, Dinshaw J. Patel and Steven E. Jacobsen. (2014) Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases. Cell, 157:1050-1060
Guillaume Moissiard, Sylvain Bischof, Dylan Husmann, William A. Pastor, Christopher J. Hale, Linda Yen, Hume Stroud, Ashot Papikian, Ajay A. Vashisht, James A. Wohlschlegel, and Steven E. Jacobsen. (2014) Transcriptional gene silencing by Arabidopsis microrchidia homologues involves the formation of heteromers. Proc. Nat. Acad. Sci. U. S. A., 111:7474-7479
Julie A. Law, Ajay A. Vashisht, James A. Wohlschlegel, Steven E. Jacobsen. (2011) SHH1, a Homeodomain Protein Required for DNA Methylation, As Well As RDR2, RDM4, and Chromatin Remodeling Factors, Associate with RNA Polymerase IV. PLoS Genetics, 7, e1002195
Julie A. Law, Israel Ausin, Lianna M. Johnson, Ajay A. Vashisht, Jian-Kang Zhu, James A. Wohlschlegel, and Steven E. Jacobsen. (2010) A Protein Complex Required for Polymerase V Transcripts and RNA Directed DNA Methylation in Arabidopsis. Current Biology, 20:951–956