题目：The fascinating diversifying force of polyploidy: Lessons from canola
主讲：Boulos Chalhoub研究员
时间：2015年10月20日上午10:30
地点：禧强楼三楼学术报告厅
组织单位：海峡联合研究院
主讲人简介：Boulos Chalhoub，男，主任研究员，博士生导师。1990年在法国图卢兹高等国立农业学校获得硕士学位，研究方向为遗传学与生物技术；1994年获得法国国立图卢兹综合理工学院博士学位，研究方向为植物遗传学与病理学；此后，分别于1995年、1997年于法国农科院植物遗传与育种实验室、细胞生物学实验室从事博士后研究；1997-1999年就职于孟山都旗下的植物遗传与生物技术实验室，担任项目负责人；1999年至今，于法国农科院植物基因组研究所植物基因组进化小组担任主任研究员。Boulos Chalhoub在基因组结构和进化领域有杰出的成就，包括油菜、小麦等多倍体复杂基因组。2014年，由Boulos Chalhoub研究员领导完成了油菜基因组的测序和分析，结果发表在《Science》期刊上。Boulos Chalhoub研究员至今已发表相关论文共计67篇，包括Science、Nature Genetics、Genome Biology、New Phytologist、Plant Cell、PNAS、Plant Journal等国际知名期刊论文。
相关代表论文：
1) # Allouis, S.M., Bellec, A., Sharp, R., Faivre Rampant, P., Mortimer, K., Pateyron, S., Foote, T.N., Griffiths, S., Caboche, M. and Chalhoub, B. (2003) Construction and characterization of a hexaploid wheat (Triticum aestivum L.) BAC library from the reference germplasm 'chinese spring'. Cereal Res. Comm. 31: 331-338.
2) # Chalhoub B., Belcram H., Caboche M. (2004). Efficient cloning of plant genomes into bacterial artificial chromosome (BAC) libraries with larger and more uniform insert size. Plant Biotechnol.2, 181-188.
3) # Safar J., Bartos J., Janda J., Bellec A., Kubalakova M., Valarik M., Pateyron S., Weiserova J., Tuskova R., Cihalikova J., Vrana J., Simkova H., Faivre-Rampant P., Sourdille P., Caboche M., Bernard M., Dolezel J., Chalhoub B. (2004). Dissecting large and complex genomes: flow sorting and BAC cloning of individual chromosomes from bread wheat. Plant J39(6), 960-968.
4) # Chantret N., Salse J., Sabot F., Rahman S., Bellec A., Laubin B., Dubois I., Dossat C., Sourdille P., Joudrier P., Gautier MF., Cattolico L., Beckert M., Aubourg S., Weissenbach J., Caboche M., Bernard M., Leroy P., Chalhoub B. (2005) Molecular Basis of Evolutionary Events That Shaped the Hardness Locus in Diploid and Polyploid Wheat Species (Triticum and Aegilops). Plant Cell. 17(4),1033-45.
5) # Gu YQ, Salse J, Coleman-Derr D, Dupin A, Crossman C, Lazo GR, Huo N, Belcram H, Ravel C, Charmet G, Charles M, Anderson OD, Chalhoub B.(2006). Types and rates of sequence evolution at the high-molecular-weight glutenin locus in hexaploid wheat and its ancestral genomes. Genetics. 174(3), 1493-1504.
6) # Charles M., Belcram H., Just J., Huneau C., Viollet A., Couloux A., Segurens B., Carter M., Huteau V., Coriton O., Appels R., Samain S., Chalhoub B (2008). Dynamics and differential proliferation of transposable elements during the evolution of the B and A genomes of wheat. Genetics. 80(2):1071-86.
7) # Charles, M., Tang, H., Belcram, H., Paterson, A., Gornicki, P., and Chalhoub, B. (2009). Sixty million years in evolution of soft grain trait in grasses: emergence of the softness locus in the common ancestor of Pooideae and Ehrhartoideae, after their divergence from Panicoideae. . Mol Biol Evol.
8) # Mestiri I., Chagué V., Tanguy A.M., Huneau C., Huteau V., Belcram H., Coriton O., Chalhoub B., Jahier J. 2010. Newly synthesized wheat allohexaploids display progenitor-dependant meiotic stability and aneuploidy but structural genomic additivity. New Phytol. 186 (1): 86-101 (DOI: 10.1111/j.1469-8137.2010.03186.x).
9) # Zhang Z, Belcram H, Gornicki P, Charles M, Just J, Huneau C, Magdelenat G, Couloux A, Samain S, Gill BS, Rasmussen JB, Barbe V, Faris JD, Chalhoub B (2011). Duplication and partitioning in evolution and function of homoeologous Q loci governing domestication characters in polyploid wheat. Proc Natl Acad Sci U S A. 2011 Oct 31. PMID: 22042872.
10) # Lu Y-H, Arnaud D., Belcram H., Falentin C., Rouault P., Piel N.,, Lucas M_O, Just J., Renard M., Delourme R., Chalhoub B. (2012). A Point Mutation in a RINGv E3 Ubiquitin Ligase Homoeologous Gene Copy Leads to Cleistogamy in the Allopolyploid Brassica napus. Plant Cell. 2012 Dec 31 PMID: 23277363
11) # Chelaifa H., Chagué V., Chalabi S., Mestiri I., Arnaud D., Deffains D., Lu Y-H, Belcram H., Huteau V., Chiquet J., Coriton O., Just J., Jahier J., Chalhoub B. (2012) Prevalence of gene expression additivity suggests an important role in the stability of wheat allohexaploids New Phytol. 2012 Dec 21. doi: 10.1111/nph.12108 PMID: 23278496
12) # Liu S, Liu Y, Yang X, Tong C, Edwards D, Parkin IA, Zhao M, Ma J, Yu J, Huang S, Wang X, Wang J, Lu K, Fang Z, Bancroft I, Yang TJ, Hu Q, Wang X, Yue Z, Li H, Yang L, Wu J, Zhou Q, Wang W, King GJ, Pires JC, Lu C, Wu Z, Sampath P, Wang Z, Guo H, Pan S, Yang L, Min J, Zhang D, Jin D, Li W, Belcram H, Tu J, Guan M, Qi C, Du D, Li J, Jiang L, Batley J, Sharpe AG, Park BS, Ruperao P, Cheng F, Waminal NE, Huang Y, Dong C, Wang L, Li J, Hu Z, Zhuang M, Huang Y, Huang J, Shi J, Mei D, Liu J, Lee TH, Wang J, Jin H, Li Z, Li X, Zhang J, Xiao L, Zhou Y, Liu Z, Liu X, Qin R, Tang X, Liu W, Wang Y, Zhang Y, Lee J, Kim HH, Denoeud F, Xu X, Liang X, Hua W, Wang X, Wang J, Chalhoub B, Paterson AH. (2014). The Brassica oleracea genome reveals the asymmetrical evolution of polyploid genomes. Nat Commun. 2014 May 23;5:3930. doi: 10.1038/ncomms4930. PMID: 24852848.
13) # Parkin IA, Koh C, Tang H, Robinson SJ, Kagale S, Clarke WE, Town CD, Nixon J, Krishnakumar V, Bidwell SL, Denoeud F, Belcram H, Links MG, Just J, Clarke C, Bender T, Huebert T, Mason AS, Pires CJ, Barker G, Moore J, Walley PG, Manoli S, Batley J, Edwards D, Nelson MN, Wang X, Paterson AH, King G, Bancroft I, Chalhoub B, Sharpe AG. (2014). Transcriptome and methylome profiling reveals relics of genome dominance in the mesopolyploid Brassica oleracea. Genome Biol. 2014 Jun 10;15(6):R77. PMID: 24916971.
14) # Chalhoub B, Denoeud F, Liu S, Parkin IA, Tang H, Wang X, Chiquet J, Belcram H, Tong C, Samans B, Corréa M, Da Silva C, Just J, Falentin C, Koh CS, Le Clainche I, Bernard M, Bento P, Noel B, Labadie K, Alberti A, Charles M, Arnaud D, Guo H, Daviaud C, Alamery S, Jabbari K, Zhao M, Edger PP, Chelaifa H, Tack D, Lassalle G, Mestiri I, Schnel N, Le Paslier MC, Fan G, Renault V, Bayer PE, Golicz AA, Manoli S, Lee TH, Thi VH, Chalabi S, Hu Q, Fan C, Tollenaere R, Lu Y, Battail C, Shen J, Sidebottom CH, Wang X, Canaguier A, Chauveau A, Bérard A, Deniot G, Guan M, Liu Z, Sun F, Lim YP, Lyons E, Town CD, Bancroft I, Wang X, Meng J, Ma J, Pires JC, King GJ, Brunel D, Delourme R, Renard M, Aury JM, Adams KL, Batley J, Snowdon RJ, Tost J, Edwards D, Zhou Y, Hua W, Sharpe AG, Paterson AH, Guan C, Wincker P. (2014). Early allopolyploid evolution in the post-Neolithic Brassica napus oilseed genome. Science. 2014 Aug 22;345(6199):950-3. doi: 10.1126/science.1253435. PMID: 25146293.